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Typhidot Test: Introduction, Procedure and Price Range

Typhidot Test
Medically reviewed by Dr Dhaval Prajapati, MD,IDCCM, EDIC, FIECMO, FCCS

If you’re looking for a comprehensive guide to the Typhidot test, you’ve come to the right place. This article will provide an overview of the Typhidot test and give some insight into what it is used for, how it works, and more. We’ll also discuss who should get this test and what it can tell us about our health. With this information in hand, you’ll be able to make informed decisions about getting tested or consulting with a doctor if needed.

What is Typhidot Test?

Have you ever heard of a typhidot test? If not, don’t worry – you’re not alone. This type of medical test is used to diagnose whether or not someone has typhoid fever, an infectious disease caused by Salmonella typhi bacteria.

The typhidot test is a simple screening blood test that can be used to detect the presence of antibodies (IgM and IgG) in the body that is created when someone has been infected with the Salmonella typhi bacteria. Usually, the test is positive within 2-3 days of infection. The results typically take anywhere from 1 to 3 hours and if they come back positive, it means that the person has typhoid fever and may need to receive treatment right away.

This test can identify infections even in those who show no symptoms or very mild symptoms so it’s important to get tested if there is any suspicion at all. Your doctor will be able to provide more information on treatment options based on your results.

When Should I Get Tested with Typhidot Test?

A Typhidot Test might be necessary if your doctor suspects that you have typhoid fever or if you have recently visited an area where the disease is prevalent. Symptoms of typhoid fever include:

  • Prolonged high temperature
  • Persistent cough
  • Extreme tiredness
  • Irregular bowel movements
  • Excessive sweating
  • Decreased appetite
  • Discomfort and Muscular pain
  • Headache

What is the Procedure of the Typhidot test?

When a Typhidot test is performed, it involves several steps to collect and analyze your blood sample. First, an elastic band or tourniquet is tied around your upper arm to make it easier to collect the blood. You will then be asked to make a tight fist, which will help fill the veins with blood.

Once the vein is located, the lab technician will clean the area with an antiseptic liquid to prevent any bacteria from entering your body. They will then insert a needle into the vein to collect the blood sample into a vacutainer tube. Once the sample is collected, the needle is removed, and the elastic band is released, allowing you to open your fist. The technician will then use a gauze pad or cotton to stop the bleeding.

After the sample is collected, it is placed in a Typhidot test kit and mixed with the chemicals or reagents provided. The kit will show results within 1-3 hours, indicating whether or not typhoid antibodies are present in the blood. It is important to note that the test results should be interpreted by a healthcare professional to ensure accurate diagnosis and appropriate treatment.

What is the Typhidot Test price?

In India, the cost of a Typhidot test can fluctuate depending on multiple factors, such as the location of the lab or hospital where it is conducted and the specific type of test being administered. However, as per the cutoff date of September 2021, the typical price range for a Typhidot test in India is between Rs. 400 to Rs. 1000. It’s essential to note that these figures are subject to change and that the most accurate and up-to-date pricing information should be confirmed with your local healthcare provider or laboratory. 

How do you Interpret the Results of the Typhidot IgM test?

The Typhidot IgM test is a diagnostic test that detects the IgM and IgG antibodies produced by the body’s immune system in response to the Salmonella Typhi bacteria, which has a 50 kilodaltons outer membrane protein. The test works by isolating the IgG and IgM antibodies using nitrocellulose strips infused with the OMP antigen.

If the test results are negative, it means that there is no presence of infection. However, if the Typhidot IgM test results are positive, it indicates a recent infection, while a positive only IgG result points to a past or chronic infection. It is crucial to consult a doctor for an accurate understanding of the test results.

What is the Difference between Widal and Typhidot test?

The difference between Widal test and Typhidot test is:

Widal Test
Typhidot Test
Used to detect Salmonella typhi and Salmonella paratyphi antigens in the blood of patients suspected of having typhoid fever.
Used to detect antibodies against Salmonella typhi in the blood of patients suspected of having typhoid fever.
Type of Test
Agglutination Test
Dot-ELISA Test
Detects the presence of antibodies in a patient's serum that react with specific antigens of S. typhi and S. paratyphi bacteria.
Detects IgM and IgG antibodies produced in response to a specific antigen of S. typhi bacteria.
Time to Results
2-3 days
1-3 hours
Low sensitivity in the early stages of the disease, but sensitivity increases after a week or two of onset.
Highly sensitive, and can detect antibodies as early as 2-3 days after the onset of symptoms.
Low specificity due to cross-reactivity with other infections caused by bacteria or viruses.
High specificity, as it only detects antibodies against S. typhi.
Relatively expensive
Interpretation of Results
Results are based on the titer of antibodies present in the patient's serum. A rising titer of antibodies over time may indicate a recent or current infection.
Results are based on the presence or absence of IgM and IgG antibodies. A positive result for both IgM and IgG indicates a recent or current infection, while a positive result for only IgG indicates a past infection or vaccination.

It’s worth noting that both tests have their own advantages and disadvantages, and the choice of which test to use may depend on a number of factors such as the stage of the disease, the prevalence of other infections in the population, and the cost of the test.

Final Thoughts

The Typhidot test is a reliable diagnostic tool for detecting typhoid fever. It is a simple and quick blood test that can accurately detect the presence of antibodies against the Salmonella typhi bacteria. It can be particularly useful in areas with limited resources or where other diagnostic tests may not be readily available.

If you have undergone a Typhidot test or any other medical test, it is important to store your reports and medical data safely for future reference. The Health-e PHR app provides a secure and convenient way to store all your health records and medical data in one place. With the Health-e PHR app, you can access your medical information anytime, anywhere, and easily share it with your healthcare providers. Download the app today and take control of your health!

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Jigar Patel is the Founder of Health-e, a HealthTech app that simplifies health records management along with providing personalized and preventative healthcare solutions. Although he has 20+ years of operations and management experience in the EPC domain, Jigar’s true passion lies in making healthcare simpler, faster and more accessible for doctors and patients alike. He strongly believes that people need to be empowered to participate in their own healthcare and is constantly thinking of ways to build this into his app. He loves to keep things simple be it in life, product design, his work or the content he develops. Being married for 10 years and having 2 kids have taught him that perspective matters, so you can always count on him to share new perspectives on various topics.